Selected Publications
2024
A role for circuitry of the cortical amygdala in excessive alcohol drinking, withdrawal, and alcohol use disorder
Xiao, T., Roland, A., Chen Y., Guffey, S., Kash T., Kimbrough A. (Alcohol)
2023
Chronic intermittent ethanol vapor exposure paired with two-bottle choice to model alcohol use disorder
Xiao, T., Chen Y., Boisvert A., Cole M., Kimbrough A. (Journal of Visualized Experiments)
Prior experience with flavored alcohol increases preference for flavored alcohol but does not influence binge-like drinking behavior in mice
Chen Y., Knorr E., Boisvert A., Xiao T., Kimbrough A. (Physiology and Behavior)
hyperconnectivity of two separate long-range cholinergic systems contributes to the reorganization of the brain functional connectivity during nicotine withdrawal in male mice
Carrette LLG., Kimbrough A., Davoudian PA., Kwan AC., Collazo A., George O. (eNeuro)
Voluntary and forced exposure to ethanol produces similar escalation of alcohol drinking but differential recruitment of brain regions related to stress, habit, and reward in male rats
de Guglielmo G., Simpson S., Kimbrough A., Conlisk D., Baker R., Cantor M., Kallupi M., George O. (Neuropharmacology)
2022
Zebrafish embryos display characteristic bioelectric signals during early development
Silic M.R., Dong Z., Chen Y., Kimbrough A., Zhang G. (Cells)
Deficiency of autism-related scn2a gene in mice disrupts sleep patterns and circadian rhythms
Ma Z., Eaton M., Liu Y., Zhang J., Chen X., Tu X., Shi Y., Que Z., Wettschurack K., Zhang Z., Shi R., Chen, Y., Kimbrough A., Lanman, N.A., Schust L., Huang Z., Yang Y. (Neurobiology of Disease)
2021
Characterization of the brain functional architecture of psychostimulant withdrawal using single-cell whole brain imaging
Kimbrough A., Kallupi M., Smith L.C., Simpson S., Collazo, A., George O. (eNeuro)
Pair bond-induced affiliation and aggression in male prairie voles elicit distinct functional connectivity in the social decision-making network
Gossman K.R., Dykstra B., García B.H. Swopes A.P., Kimbrough A., Smith A.S. (Frontiers in Neuroscience)
The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches
Simpson S., Chen Y., Wellmeyer E., Smith L.C., Aragon Montes B., George O., Kimbrough A. (Frontiers in Systems Neuroscience)
The cocaine and oxycodone biobanks, two repositories from genetically diverse and behaviorally characterized rats for the study of addiction
Carrette L.L., de Guglielmo G, Kallupi M, Maturin L, Brennan M, Boomhower B, Conlisk D, Sedighim S, Tieu L, Fannon M.J., Velarde N, Kononoff J, Kimbrough A, Simpson S, Smith L.C., Shankar K, Ramirez F Jr, Chitre A.S., Lin B, Polesskaya O, Solberg Woods L.C., Palmer A.A., George O. (eNeuro)
2020
Leveraging neural networks in preclinical alcohol research
Smith. L.C. and Kimbrough A. (Brain Sciences)
Depletion of the Microbiome Alters the Recruitment of Neuronal Ensembles of Oxycodone Intoxication and Withdrawal
Simpson S., Kimbrough A., Boomhower B., McLellan R., Hughes M., Shankar K., de Guglielmo G., George O. (eNeuro)
Role of corticotropin-releasing factor in alcohol and nicotine addiction
Simpson S., Shankar K., Kimbrough A., George O. (Brain Research)
Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior
Lee, C.H., George, O., Kimbrough, A. (Pharmacology, Biochemistry & Behavior)
Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats
Kimbrough, A.*, Kononoff, J.*, Simpson, S.*, Kallupi, M., Sedighim, S., Palomino, K., Conlisk, D., Momper, J.D., de Guglielmo, G., George, O. (Psychopharmacology)
Brain-wide functional architecture remodeling by alcohol dependence and abstinence
Kimbrough A., Lurie D.J., Collazo A., Kreifeldt M., Sidhu H., Macedo G.C., D'Esposito M., Contet C., George O. (Proceedings of the National Academy of Sciences USA)
2019
Forty-eight hour conditioning produces a robust long lasting flavor preference in rats
Kimbrough A., Houpt, T.A. (Appetite)
2018
Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood
Kononoff, J., Melas, P., de Guglielmo, G., Kallupi, M., Kimbrough, A., Scherma, M., Kandel, D.B., Kandel, E.R., George, O. (Scientific Reports)
Systemic and intra-habenular activation of the orphan G protein-coupled receptor GPR139 decreases compulsive- like alcohol drinking and hyperalgesia in alcohol-dependent rats.
Kononoff, J., Kallupi, M., Kimbrough, A., Conlisk, D., de Guglielmo, G., George, O. (eNeuro)
2017
Intermittent access to ethanol drinking facilitates the transition to excessive drinking after chronic intermittent ethanol vapor exposure
Kimbrough, A., Kim, S., Cole, M., Brennan, M. George, O. (Alcoholism: Clinical and Experimental Research)
CRF1- dependent increases in irritability-like behavior during abstinence from chronic intermittent ethanol vapor exposure
Kimbrough, A., de Guglielmo, G., Kononoff, J., Kallupi, M., Zorrilla, E.P., George, O. (Alcoholism: Clinical and Experimental Research)